protein

VCAM-1/CD106 Protein, Mouse (HEK293, His)

HY-P73470

5 μg;10 μg;50 μg;100 μg

50;85;235;400 USD

VCAM-1/CD106 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

50;85;235;400 USD

VCAM-1 protein is a member of the immunoglobulin superfamily.It can act as a regulator of capillary formation and liver fibrosis, and can promote liver fibrosis.VCAM-1 Protein plays an important role in immune response and inflammatory response.VCAM-1/CD106 Protein, Mouse (HEK293, His) is the recombinant mouse-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-His labeled tag.

Mouse

VCAM-1 protein supports leukocyte adhesion by binding to α4β1 integrin and is crucial for the recruitment of monocytes and lymphocytes during inflammation [1] [5] . VCAM-1 Protein is a regulator of capillary formation and hepatic fibrosis in liver sinusoidal endothelial cells (LSECs). VCAM-1 Protein can activate the Yes-associated protein 1 pathway and induce fibrosis phenotypes in HSCs [2] . VCAM-1 Protein causes persistent inflammation by inhibiting effective T cell apoptosis [3] . VCAM-1 protein causes persistent inflammation by inhibiting the apoptosis of effector T cells [3] . VCAM-1 protein plays an important role in regulating immune response and inflammatory response to viral infection [4] . VCAM-1 Protein is necessary for smooth muscle cell migration. Targeting VCAM-1 expression can effectively prevent and treat atherosclerosis and restenosis [5] .

Vascular Cell Adhesion Protein 1; VCAM-1; INCAM-100; CD106; L1CAM

Greater than 95% as determined by reducing SDS-PAGE or Tris-Bis PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.