protein

TrkC Protein, Human (HEK293, His)

HY-P73465

5 μg;10 μg;50 μg;100 μg

45;72;185;300 USD

TrkC Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

45;72;185;300 USD

TrkC Protein, a receptor tyrosine kinase, crucially contributes to nervous system and potential heart development. Upon NTF3/neurotrophin-3 binding, TrkC undergoes autophosphorylation, activating pathways like phosphatidylinositol 3-kinase/AKT and MAPK. These pathways regulate cell survival and differentiation, emphasizing TrkC's pivotal role in essential cellular processes during development. TrkC Protein, Human (HEK293, His) is the recombinant human-derived TrkC protein, expressed by HEK293 , with C-His labeled tag.

Human

TrkC Protein, a receptor tyrosine kinase, plays a crucial role in nervous system and potential heart development. Upon binding to its ligand NTF3/neurotrophin-3, TrkC undergoes autophosphorylation, initiating various signaling pathways such as the phosphatidylinositol 3-kinase/AKT and the MAPK pathways. These pathways are instrumental in regulating cell survival and differentiation, highlighting the pivotal role of TrkC in orchestrating essential cellular processes during development.

TrkC; NT-3 Growth Factor Receptor; NTRK3; TRKC

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 5% Trehalose, 5% Manitol, 0.01% Tween-80 or 20 mM PB, 150 mM Nacl, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.