protein

TFPI Protein, Mouse (HEK293, His)

HY-P73425

5 μg;10 μg;50 μg

118;200;550 USD

TFPI Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

118;200;550 USD

TFPI Protein, a potent inhibitor in the coagulation cascade, directly inhibits factor X (Xa). In a Xa-dependent manner, it also inhibits the activity of VIIa/tissue factor, potentially forming a quaternary complex with Xa, TFPI, VIIa, and tissue factor. Beyond its antithrombotic role, TFPI associates with plasma lipoproteins, indicating its regulatory involvement in hemostasis and clotting processes. TFPI Protein, Mouse (HEK293, His) is the recombinant mouse-derived TFPI protein, expressed by HEK293 , with C-His labeled tag.

Mouse

TFPI protein serves as a potent inhibitor in the coagulation cascade by directly inhibiting factor X (Xa). In a Xa-dependent manner, it further inhibits the activity of VIIa/tissue factor, potentially through the formation of a quaternary complex involving Xa, TFPI, VIIa, and tissue factor. Beyond its role in antithrombotic action, TFPI exhibits the capability to associate with lipoproteins in plasma, suggesting its involvement in regulating hemostasis and clotting processes.

Tissue factor pathway inhibitor; TFPI; EPI; LACI

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4

Shipping with dry ice.