protein

RANKL/TNFSF11 Protein, Human (HEK293, hFc)

HY-P73387

10 μg;50 μg;100 μg

100;250;400 USD

RANKL/TNFSF11 Protein, Human (HEK293, hFc)

Protein

HEK293

10 μg;50 μg;100 μg

100;250;400 USD

RANKL (TNFSF11), a type II transmembrane protein, is a receptor activator of NF-κB (RANK) ligand. RANKL is an activator of RANK. When binding to RANK, it induces the differentiation of monocyte/macrophage-lineage cells into osteoclasts and leads to osteoclast precursor maturation. RANKL is critical for osteoclasts maturation, bone modeling, and bone remodeling, as well as the development of lymph nodes (LNs). RANKL/TNFSF11 Protein, Human (HEK293, hFc) is a recombinant human RANKL (G64-D245) with N-terminal hFc tag, which is produced in HEK293.