CD47 Protein, Human (HEK293, Fc) | MedChem Express LLC HY-P7335 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

CD47 Protein, Human (HEK293, Fc)

catalog :

HY-P7335

quantity :

10 μg;50 μg

price :

120;320 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7335

Product Name :

CD47 Protein, Human (HEK293, Fc)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

120;320 USD

list of Pubmed id :

384647033

Product Description :

CD47 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-terminal human IgG1 Fc fragment produced in HEK293 cells. CD47 is a prominent target in cancer immunotherapy.

SpeciesSummary :

Human

Background :

Targeting CD47 is in the spotlight of cancer immunotherapy. Blocking CD47 triggers the recognition and elimination of cancer cells by the innate immunity. The CD47/SIRP-α axis has been established as an important regulator of innate anti-cancer immunity, with many if not all malignancies overexpressing the receptor CD47 that binds to phagocyte-expressed SIRP-α [1] .

ALTnames :

rHuCD47, Fc Chimera; MER6; IAP; OA3

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage