protein

NRG1-beta 1 Protein, Human (245a.a, HEK293, Fc)

HY-P73329

2 μg;10 μg;50 μg;100 μg;1 mg

35;65;180;300;1500 USD

NRG1-beta 1 Protein, Human (245a.a, HEK293, Fc)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;1 mg

35;65;180;300;1500 USD

HRG1-β1 belongs to a family of structurally-related polypeptide growth factors derived from alternatively spliced genes, induces Fn14 expression in MCF7 cells. NRG1-beta 1 Protein, Human (245a.a, HEK293, Fc) is the recombinant human-derived NRG1-beta 1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of NRG1-beta 1 Protein, Human (245a.a, HEK293, Fc) is 245 a.a., with molecular weight of 58-83 kDa.

Human

HRG1-β1 activates HER2/HER3 signaling and up-regulate Fn14 gene expression in parental MCF7 cells. HRG1-β1-mediated Fn14 up-regulation in MCF7/HER2-18 cells is required for maximal MMP-9 production.

Pro-neuregulin-1; Neuregulin-1; ARIA; HRG; NRG1; GGF; HGL; HRGA; NDF; SMDF

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.