protein

NRG1-beta 2 Protein, Human

HY-P73304

2 μg;10 μg;50 μg;100 μg;500 μg

35;85;250;400;950 USD

NRG1-beta 2 Protein, Human

proteins

E. coli

2 μg;10 μg;50 μg;100 μg;500 μg

35;85;250;400;950 USD

HRG1-β1 belongs to a family of structurally-related polypeptide growth factors derived from alternatively spliced genes, induces Fn14 expression in MCF7 cells. NRG1-beta 2 Protein, Human is the recombinant human-derived NRG1-beta 2 protein, expressed by E. coli , with tag free. The total length of NRG1-beta 2 Protein, Human is 61 a.a., with molecular weight of ~7.0 kDa.

Human

HRG1-β1 activates HER2/HER3 signaling and up-regulate Fn14 gene expression in parental MCF7 cells. HRG1-β1-mediated Fn14 up-regulation in MCF7/HER2-18 cells is required for maximal MMP-9 production.

NRG-1 EGF-like domain beta 2; Beta2; Neuregulin-1 beta 2

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution in 20 mM PB, pH 7.0, containing 0.5 % HAS and 2 % mannitol or PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.