protein

MMP-9 Protein, Rat (HEK293, His)

HY-P73301

5 μg;10 μg;50 μg;100 μg

105;175;490;830 USD

MMP-9 Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

105;175;490;830 USD

Matrix metalloproteinase-9 (Mmp9) is a member of the matrix metalloproteinase (MMP) family. Mmp9 is secreted as inactive proproteins which are activated when cleaved by extracellular proteinases to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mmp9 is also involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow. MMP-9 Protein, Rat (HEK293, His) is the recombinant rat-derived MMP-9 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of MMP-9 Protein, Rat (HEK293, His) is 689 a.a., with molecular weight of approximately 95 kDa.

Rat

Matrix metalloproteinase-9 (Mmp9) is a member of the matrix metalloproteinase (MMP) family, which are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, wound repair, and tissue remodeling, as well as in disease processes, such as arthritis, progression of atherosclerosis and tumor invasion. Mmp9 is secreted as inactive proproteins which are activated when cleaved by extracellular proteinases to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mmp9 is also involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow. Mmp9 implicates in several diseases, including Down syndrome; anodontia; artery disease; autoimmune disease; and chronic obstructive pulmonary disease [1] [2] .

Matrix metalloproteinase-9; MMP-9; Gelatinase B; GELB; CLG4B

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 50 mM MES, 100 mM NaCl, 1 mM CaCl 2 , 10% Glycerol, pH 7.4 (Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.) or 50 mM MES, 100 mM NaCl, 1 mM CaCL 2 , pH 7.4.

Room temperature in continental US; may vary elsewhere.