protein

Betacellulin/BTC Protein, Mouse (N-His)

HY-P7329

2 μg;10 μg;50 μg;100 μg

35;80;240;400 USD

Betacellulin/BTC Protein, Mouse (N-His)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

35;80;240;400 USD

384647027

Probetacellulin Protein, Mouse, induces differentiation of pancreatic β-cells and promotes regeneration of β-cells in experimental diabetes.

Mouse

Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, induces differentiation of pancreatic β-cells and promotes regeneration of β-cells in experimental diabetes. BTC stimulates DNA synthesis in fibroblasts and vascular smooth muscle cells. BTC plays a role in regulating growth and/or differentiation of endocrine precursor cells of the fetal pancreas. BTC is found to convert amylase-secreting pancreatic AR42J cells into insulin-producing cells and to have a mitogenic effect in human undifferentiated pancreatic epithelial cells [1] .

rMuBetacellulin; BTC

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, 200 mM arginine, pH 8.0 or PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.