protein

Kallikrein-1 Protein, Human (240a.a, HEK293, His)

HY-P73262

50 μg

550 USD

Kallikrein-1 Protein, Human (240a.a, HEK293, His)

proteins

HEK293

50 μg

550 USD

Kallikrein-1 protein cleaves bonds in kininogen to release Lys-bradykinin. It also cleaves Neisseria meningitidis NHBA in saliva during microbial infection. Kallikrein-1 Protein, Human (240a.a, HEK293, His) is the recombinant human-derived Kallikrein-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Kallikrein-1 Protein, Human (240a.a, HEK293, His) is 240 a.a., with molecular weight of ~50 kDa.

Human

Kallikrein-1 protein functions by cleaving Met-Lys and Arg-Ser bonds in kininogen, leading to the release of Lys-bradykinin. In the context of microbial infection, it plays a role in cleaving Neisseria meningitidis NHBA in saliva, with Neisseria being an obligate commensal of the nasopharyngeal mucosa.

Kallikrein 1; Kidney/pancreas/salivary gland kallikrein; KLK1; Klk6; KLKR

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.