protein

IL-6R alpha Protein, Human (HEK293, Fc)

HY-P73222

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;55;150;255;1050;1800 USD

IL-6R alpha Protein, Human (HEK293, Fc)

Protein

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;55;150;255;1050;1800 USD

IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (M1-P365) is soluble form and produced in HEK293 cells with a C-Terminal hFc-tag.