B7-2/CD86 Protein, Human (HEK293, Fc) | MedChem Express LLC HY-P7322 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

B7-2/CD86 Protein, Human (HEK293, Fc)

catalog :

HY-P7322

quantity :

10 μg;50 μg;100 μg

price :

108;280;450 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7322

Product Name :

B7-2/CD86 Protein, Human (HEK293, Fc)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg;100 μg

List Price :

108;280;450 USD

list of Pubmed id :

384647020

Product Description :

B7-2/CD86 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-termimal human IgG1 Fc fragment produced in HEK293 cells. B7-2 (CD86) is a costimulatory molecule expressed by antigen-presenting cells (APCs), which interacts with CD28 for T-cell activation and survival and with CTLA4 for immune regulation.

SpeciesSummary :

Human

Background :

CD86 is a transmembrane region, and a longer cytoplasmic domain than CD80. CD86 is constitutively expressed on interdigitating dendritic cells (DCs), Langerhans cells, peripheral blood DCs, memory B cells and germinal center B cells, and macrophages. CD86 is rapidly upregulated on B cells following activation by cross-linking of the Ig receptor or the addition of a variety of cytokines [1] .

ALTnames :

rHuB7-2/CD86, Fc Chimera; Activation B7-2 antigen; B70; BU63; CD86; CD28LG2

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS, 5% trehalose and mannitol.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage