B7-1/CD80 Protein, Human (HEK293, Fc) | MedChem Express LLC HY-P7321 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

B7-1/CD80 Protein, Human (HEK293, Fc)

catalog :

HY-P7321

quantity :

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

price :

35;60;150;240;500;850;1450 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7321

Product Name :

B7-1/CD80 Protein, Human (HEK293, Fc)

Product Type :

proteins

Host Species :

HEK293

Size :

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

List Price :

35;60;150;240;500;850;1450 USD

list of Pubmed id :

384647019

Product Description :

B7-1/CD80 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-termimal human IgG1 Fc fragment produced in HEK293 cells. CD80 is a costimulatory molecule known for its role in T-cell activation and also in regulating normal and malignant B cellsactivity.

SpeciesSummary :

Human

Background :

CD80 (B7-1) and CD86 (B7-2) are expressed as cell surface molecules by APCs and are responsible for delivering additional or second signals to T cells when they interact with their ligands CD28 and CD152 (CTLA-4). Expression of B7.1 (CD80) and B7.2 (CD86), two related moleculesbelonging to the Ig superfamily, appears crucial to the ability of the APCs to activate T cells [1] .

ALTnames :

rHuB7-1/CD80, Fc Chimera; BB1; CD28LG; CD28LG1; LAB7

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage