product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
EGFR Protein, Human (621a.a, Sf9, His)
catalog :
HY-P7316
quantity :
10 μg;50 μg
price :
85;240 USD
product information
Catalog Number :
HY-P7316
Product Name :
EGFR Protein, Human (621a.a, Sf9, His)
Product Type :
proteins
Host Species :
Sf9 insect cells
Size :
10 μg;50 μg
List Price :
85;240 USD
list of Pubmed id :
384647014
Product Description :
EGFR Protein, Human (Sf9, His) is a glycosylated polypeptide chain with the C-termimal 6×His Tag produced in Sf9 insect cells. EGFR, belongs to a family of tyrosine kinase receptors, plays important roles in cell growth and differentiation.
SpeciesSummary :
Human
Background :
Epidermal growth factor receptor (EGFR) belongs to a family of tyrosine kinase receptors including Human EGF Receptors (HER) 2, 3, and 4 which all play important roles in cell growth and differentiation. Their primary ligands are EGF, Heparin-Binding EGF and Transforming Growth Factor α. Upon ligand binding, EGFR undergoes asymmetric dimerization, composed of an “activator” and a “receiver”. EGFR and its family members are disregulated in numerous cancers. In particular, EGFR is overexpressed in many epithelial solid tumors.
ALTnames :
rHuEGFR, His; ErbB1; HER1; ERBB
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Buffer :
Lyophilized after extensive dialysis against PBS.
Storage :
Room temperature in continental US; may vary elsewhere.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA