protein

IFN-beta Protein, Rhesus Macaque (HEK293, Fc)

HY-P73132

100 μg

380 USD

IFN-beta Protein, Rhesus Macaque (HEK293, Fc)

proteins

HEK293

100 μg

380 USD

IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family. IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway. IFN-beta Protein regulates mitochondrial fission through STAT5, PGAM5, and Drp1 to rescue neurodegeneration. IFN-beta Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein, expressed by HEK293 , with C-mFc labeled tag.

Rhesus Macaque

Interferon (IFN) constitutes a family of cytokines that naturally secrete immunoregulatory functions. They boost macrophages to destroy tumor cells, viruses and bacteria. There are two types of IFN: Type 1 includes IFN-α and β, and type 2 consists only of IFN-γ. IFN-beta and IFN-gamma have opposite effects, IFN-gamma promotes the inflammatory response, while IFN-beta is primarily anti-inflammatory. Exogenous IFN-beta reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway. IFN-beta rescues neurodegeneration by regulating mitochondrial fission through STAT5, PGAM5, and Drp1 [1] [2] [3] .

Interferon beta; IFN-beta; IFNB1; IFB; IFNB

Greater than 85% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.