protein

HAI-1 Protein, Mouse (Fc)

HY-P73092

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

HAI-1 Protein, Mouse (Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

The HAI-1 protein is a multifaceted inhibitor that potently inhibits HGFAC and protects against serine proteases such as ST14/matriptase and TMPRSS13. Through its BPTI/Kunitz inhibitor 1 domain, HAI-1 cleverly coordinates inhibition, engaging in a delicate molecular dance with HGFAC and TMPRSS13. HAI-1 Protein, Mouse (Fc) is the recombinant mouse-derived HAI-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of HAI-1 Protein, Mouse (Fc) is 414 a.a., with molecular weight of ~73.2 kDa.

Mouse

HAI-1, a multifaceted protein, stands as a potent inhibitor in diverse cellular contexts. Notably, it acts as a robust inhibitor of HGFAC, exerting its regulatory influence on this pivotal factor. Functioning as a guardian against serine protease activities, HAI-1 demonstrates inhibitory effects on ST14/matriptase and TMPRSS13, skillfully wielding its BPTI/Kunitz inhibitor 1 domain. The intricate molecular ballet involves direct interactions with HGFAC and TMPRSS13, orchestrating a nuanced dance that not only inhibits but also promotes specific cellular processes. The interplay with TMPRSS13 underscores HAI-1's role in orchestrating the phosphorylation and cellular localization of this serine protease. In these multifaceted interactions, HAI-1 emerges as a versatile guardian, finely tuning the delicate balance of protease activities in cellular environments.

Kunitz-type protease inhibitor 1; HAI-1; SPINT1; HAI1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.