protein

GM-CSF Protein, Mouse (HEK293, Fc)

HY-P73082

5 μg;10 μg;50 μg;100 μg

67;114;320;544 USD

GM-CSF Protein, Mouse (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

67;114;320;544 USD

The GM-CSF protein acts as a potent cytokine that coordinates the growth and differentiation of hematopoietic precursor cells of different lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer and its signaling is mediated through a dodecamer complex. GM-CSF Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived GM-CSF protein, expressed by HEK293 , with N-hFc labeled tag. The total length of GM-CSF Protein, Mouse (HEK293, Fc) is 124 a.a., with molecular weight of 45-60 kDa.

Mouse

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) is a cytokine known for its role in stimulating the growth and differentiation of hematopoietic precursor cells across various lineages, including granulocytes, macrophages, eosinophils, and erythrocytes. Structurally, GM-CSF exists as a monomer. Its signaling mechanism involves interaction with the GM-CSF receptor complex, which forms a dodecamer consisting of two head-to-head hexamers involving two alpha, two beta, and two ligand subunits. Through this intricate receptor complex, GM-CSF orchestrates the regulation of hematopoiesis, contributing to the development and maturation of diverse blood cell types.

Granulocyte-macrophage colony-stimulating factor; GM-CSF; CSF; CSF-2

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, PH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.