protein

Animal-Free TRAIL/TNFSF10 Protein, Human (His)

HY-P7306AF

2 μg;10 μg;50 μg

40;108;300 USD

Animal-Free TRAIL/TNFSF10 Protein, Human (His)

proteins

E. coli

2 μg;10 μg;50 μg

40;108;300 USD

TRAIL/TNFSF10 protein is a cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly TNFRSF11B/OPG. It induces apoptosis, a process that can be mediated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG, which lack the ability to induce apoptosis. Animal-Free TRAIL/TNFSF10 Protein, Human (His) is the recombinant human-derived animal-FreeTRAIL/TNFSF10 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free TRAIL/TNFSF10 Protein, Human (His) is 168 a.a., with molecular weight of ~20.33 kDa.This product is for cell culture use only.

Human

TRAIL/TNFSF10 protein, a cytokine, binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly TNFRSF11B/OPG. It induces apoptosis, a process that may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG, which lack the ability to induce apoptosis. Existing as a homotrimer, one TNFSF10 homotrimer interacts with three TNFSF10A monomers, and similarly, one TNFSF10 homotrimer interacts with three TNFSF10B monomers. This intricate interaction underlines the complexity of TRAIL/TNFSF10-mediated apoptotic signaling, showcasing its ability to engage multiple receptors and form distinct molecular configurations for its biological activity.

TNFSF10; Apo2 Ligand; TL2; Apo2L; CD253

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a solution containing 1X PBS, pH 8.0, trehalose.

Room temperature in continental US; may vary elsewhere.