protein

E-Selectin/CD62E Protein, Mouse (HEK293, His)

HY-P73042

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

45;75;205;350;980;1660 USD

E-Selectin/CD62E Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

45;75;205;350;980;1660 USD

E-Selectin/CD62E protein, a cell-surface glycoprotein, mediates the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1. It also potentially contributes to capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2. These multifaceted interactions highlight E-Selectin's role in cell adhesion and its potential influence on vascular development. E-Selectin/CD62E Protein, Mouse (HEK293, His) is the recombinant mouse-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-His, C-10*His labeled tag.

Mouse

E-Selectin/CD62E protein, a cell-surface glycoprotein, plays a crucial role in immunoadhesion by mediating the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1. Beyond its involvement in immune responses, E-Selectin may also contribute to capillary morphogenesis. The protein interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, with SELPLG sulfation seemingly not required for this interaction. These interactions highlight the multifaceted roles of E-Selectin in mediating cell adhesion events and potentially influencing processes related to vascular development.

E-selectin; ELAM-1; LECAM2; CD62E; SELE

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.