protein

EphA2 Protein, Human (Biotinylated, HEK293, His-Avi)

HY-P72992

20 μg;100 μg

286;800 USD

EphA2 Protein, Human (Biotinylated, HEK293, His-Avi)

proteins

HEK293

20 μg;100 μg

286;800 USD

The EphA2 protein is an important member of the ephrin receptor subfamily that mediates developmental events, particularly in the nervous system. It has a single kinase domain and an extracellular region that binds ephrin-A ligands. EphA2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived EphA2 protein, expressed by HEK293 , with C-6*His, C-Avi labeled tag. The total length of EphA2 Protein, Human (Biotinylated, HEK293, His-Avi) is 511 a.a., with molecular weight of ~59.4 kDa.

Human

EphA2 Protein, a member of the ephrin receptor subfamily within the protein-tyrosine kinase family, plays a crucial role in mediating developmental events, particularly within the nervous system. Featuring a single kinase domain and an extracellular region with a Cys-rich domain and 2 fibronectin type III repeats, EPH receptors are involved in binding ephrin-A and ephrin-B ligands. EphA2 specifically binds ephrin-A ligands and displays broad expression across various tissues, including esophagus (RPKM 37.8), urinary bladder (RPKM 18.3), and 21 other tissues. Additionally, mutations in this gene are associated with certain genetically-related cataract disorders, highlighting its significance in both developmental processes and ocular health.

Ephrin type-A receptor 2; Epithelial cell kinase; EPHA2; ECK

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.