product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
EGF Protein, Canine (P.pastoris)
catalog :
HY-P72980
quantity :
5 μg;10 μg;20 μg;50 μg
price :
42;65;105;200 USD
product information
Catalog Number :
HY-P72980
Product Name :
EGF Protein, Canine (P.pastoris)
Product Type :
proteins
Host Species :
P. pastoris
Size :
5 μg;10 μg;20 μg;50 μg
List Price :
42;65;105;200 USD
Product Description :
The EGF protein plays a key role in promoting the growth of a variety of epidermal and epithelial tissues in vivo and in vitro and in stimulating the proliferation of certain fibroblasts in cell culture. In addition, it also has the effect of magnesium-stimulating hormone, causing magnesium reabsorption in the renal distal convoluted tubule through the participation of EGFR and the activation of magnesium channel TRPM6. EGF Protein, Canine (P.pastoris) is the recombinant canine-derived EGF protein, expressed by P. pastoris , with tag free. The total length of EGF Protein, Canine (P.pastoris) is 52 a.a., with molecular weight of ~6.2 kDa.
SpeciesSummary :
Canine
Background :
Epidermal Growth Factor (EGF) is a potent stimulator of growth for various epidermal and epithelial tissues both in vivo and in vitro, as well as some fibroblasts in cell culture. This multifunctional protein plays a vital role in cellular processes, particularly in promoting the proliferation and development of tissues. Beyond its role in tissue growth, EGF acts as a magnesiotropic hormone, facilitating magnesium reabsorption in the renal distal convoluted tubule through the engagement of EGFR and activation of the magnesium channel TRPM6. Additionally, EGF interacts with EGFR, promoting EGFR dimerization, and engages with RHBDF1 and RHBDF2, potentially influencing EGF's intracellular trafficking and degradation pathways. These interactions underline the complex and versatile functions of EGF in both growth and signaling processes within the cell.
ALTnames :
Pro-epidermal growth factor; Urogastrone; EGF; HOMG4
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Buffer :
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Storage :
Shipping with dry ice
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA