protein

CSF1R Protein, Rat (HEK293, His)

HY-P72955

5 μg;10 μg;50 μg;100 μg

40;65;180;290 USD

CSF1R Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

40;65;180;290 USD

CSF1R Protein is a cell surface receptor with high a affinity for a variety of polypeptide growth factors, cytokines, and hormones. CSF1R Protein participate in PLCG2/PKA/UCP2 signaling pathway to reduce oxidative stress and neuronal apoptosis in rat models with neonatal HIE. The blocking of the CSF1R signal is associated with tumorigenesis. CSF1R Protein, Rat (HEK293, His) is the recombinant rat-derived CSF1R protein, expressed by HEK293 , with C-His labeled tag. The total length of CSF1R Protein, Rat (HEK293, His) is 491 a.a., with molecular weight of 69-89 kDa.

Rat

Receptor protein-tyrosine kinase is a cell surface receptor with a high affinity for a variety of polypeptide growth factors, cytokines, and hormones. Homologous with human CSF1R (colony-stimulating factor 1 receptor). CSF1R has macrophage colony-stimulating factor receptor activity, protein homodimerization activity and protein phosphatase binding activity. CSF1R is involved in the positive regulation of osteoclast differentiation and bone resorption. CSF1R participates in PLCG2/PKA/UCP2 signaling pathway to reduce oxidative stress and neuronal apoptosis in rat models with neonatal HIE. The blocking of the CSF1R signal can inhibit tumor-infiltrating myeloid cells and improve the therapeutic effect of radiotherapy for prostate cancer. In INS-1E beta-cells, Erk1/2 phosphorylation is activated by construction of the CSF1R/IRR receptor [1] [2] [3] [4] .

Macrophage colony-stimulating factor 1 receptor; CSF-1R; M-CSF-R; CD115; CSF1R; FMS

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice