protein

Coagulation Factor II/F2 Protein, Mouse (HEK293, His)

HY-P72944

5 μg;10 μg;50 μg;100 μg

50;80;225;385 USD

Coagulation Factor II/F2 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

50;80;225;385 USD

Coagulation Factor II/F2, also known as thrombin, functions as a pivotal serine protease. Its enzymatic action involves cleaving bonds after Arg and Lys residues, facilitating the conversion of fibrinogen to fibrin. Thrombin additionally activates key factors like V, VII, VIII, XIII, and, in conjunction with thrombomodulin, protein C. Beyond blood homeostasis, thrombin plays a role in inflammation and the complex dynamics of wound healing. Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor II/F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is 594 a.a., with molecular weight of ~85 kDa.

Mouse

The Coagulation Factor II/F2 protein, commonly known as thrombin, plays a pivotal role in various physiological processes. Operating as a serine protease, thrombin cleaves bonds following Arg and Lys residues, leading to the conversion of fibrinogen into fibrin. Moreover, thrombin activates several crucial factors, including V, VII, VIII, XIII, and, when in conjunction with thrombomodulin, protein C. Beyond its fundamental role in blood homeostasis, thrombin also contributes to inflammation and the intricate process of wound healing.

Prothrombin; Coagulation factor II

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.