protein

CD64 Protein, Human (Biotinylated, 272a.a, HEK293, His-Avi)

HY-P72926

20 μg

430 USD

CD64 Protein, Human (Biotinylated, 272a.a, HEK293, His-Avi)

proteins

HEK293

20 μg

430 USD

CD64 protein, a high affinity receptor, mediates IgG effector functions, triggering antibody-dependent cellular cytotoxicity (ADCC). It interacts with IGHG1 and forms a signaling complex with FCERG1, contributing to immune responses. CD64 also interacts with FLNA, EPB41L2, LAT, PPL, HCK, and LYN to prevent degradation of FCGR1A and regulate immune function. CD64 Protein, Human (Biotinylated, 272a.a, HEK293, His-Avi) is the recombinant human-derived CD64 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

Human

CD64 protein is a high affinity receptor for the Fc region of immunoglobulins gamma. It plays a role in both innate and adaptive immune responses. CD64 mediates IgG effector functions on monocytes, triggering antibody-dependent cellular cytotoxicity (ADCC) against virus-infected cells. It interacts with IGHG1 and forms a functional signaling complex with FCERG1. CD64 also interacts with FLNA, preventing degradation of FCGR1A. Additionally, it interacts with EPB41L2, LAT, PPL, HCK, and LYN, contributing to its diverse functions in immune regulation.

High affinity immunoglobulin gamma Fc receptor I; Fcgr1; FcRI; CD64

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.