protein

CD4 Protein, Mouse (HEK293, His)

HY-P72904

5 μg;10 μg;50 μg;100 μg;500 μg

35;60;170;290;900 USD

CD4 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg

35;60;170;290;900 USD

CD4 is a glycoprotein critical in immune responses that binds to interleukin-16 and forms a homodimer. It enhances helper T cell-mediated immune responses and regulates processes such as defense against Gram-negative bacteria and calcium signaling. CD4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD4 protein, expressed by HEK293 , with C-His, C-6*His labeled tag. The total length of CD4 Protein, Mouse (HEK293, His) is 368 a.a., with molecular weight of 43-60 kDa.

Mouse

CD4, a key glycoprotein involved in immune responses, is predicted to perform various functions, including interleukin-16 binding activity, interleukin-16 receptor activity, and protein homodimerization activity. Playing a critical role in helper T cell enhancement of the adaptive immune response, CD4 acts upstream of processes such as the defense response to Gram-negative bacteria, positive regulation of calcium-mediated signaling, and positive regulation of peptidyl-tyrosine phosphorylation. Positioned in the endoplasmic reticulum, on the external side of the plasma membrane, and within membrane rafts, CD4 exhibits biased expression in different tissues, particularly evident in the thymus with an expression level of RPKM 167.0, and the spleen with RPKM 15.0, underscoring its significance in immune function and its potential involvement in immunodeficiency 79.

T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD4

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.