protein

MME Protein, Human (HEK293, Tag Free)

HY-P72876A

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

72;115;300;480;1200;1800 USD

MME Protein, Human (HEK293, Tag Free)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

72;115;300;480;1200;1800 USD

MME proteins exhibit thermolysin-like specificity and primarily degrade polypeptides of up to 30 amino acids. Crucially, it plays a key role in cleaving the Gly-Phe bond to degrade opioid peptides, including Met-enkephalin and Leu-enkephalin. MME Protein, Human (HEK293) is the recombinant human-derived MME protein, expressed by HEK293 , with tag free. The total length of MME Protein, Human (HEK293) is 699 a.a., with molecular weight of 80-100 kDa.

Human

The MME Protein demonstrates a thermolysin-like specificity, predominantly acting on polypeptides of up to 30 amino acids. Biologically crucial, it plays a key role in the degradation of opioid peptides, including Met- and Leu-enkephalins, achieved through the cleavage of a Gly-Phe bond. Additionally, MME catalyzes the cleavage of bradykinin, substance P, and neurotensin peptides and is capable of cleaving angiotensin-1, angiotensin-2, and angiotensin 1-9. The protein is involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Furthermore, MME displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Neprilysin; Atriopeptidase; CALLA; NEP; SFE; CD10; MME; EPN

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.