protein

Carbonic Anhydrase 2 Protein, Mouse (His)

HY-P72861

5 μg;10 μg;50 μg;100 μg

49;84;235;400 USD

Carbonic Anhydrase 2 Protein, Mouse (His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

49;84;235;400 USD

Carbonic Anhydrase 2 Protein is a member of the carbonic anhydrase isozyme family, responsible for catalyzing the reversible hydration of carbon dioxide. Mutations in CA2 are linked to osteopetrosis and renal tubular acidosis. The gene exhibits biased expression in various tissues, notably in the stomach and colon. CA2 plays vital role in the regulation of ion transport and pH balance and is involved in many biological processes. Carbonic Anhydrase 2 Protein, Mouse (His) is the recombinant mouse-derived Carbonic Anhydrase 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carbonic Anhydrase 2 Protein, Mouse (His) is 259 a.a., with molecular weight of 30-35 kDa.

Mouse

Carbonic Anhydrase 2 (CA2) is a member of the carbonic anhydrase isozyme family, responsible for catalyzing the reversible hydration of carbon dioxide. Dysregulation of this enzyme is linked to conditions such as osteopetrosis and renal tubular acidosis. Two transcript variants encoding distinct isoforms have been identified. In addition to its fundamental role in carbon dioxide metabolism, the protein exhibits biased expression in various tissues, with notable levels in the stomach and colon, as well as eight other tissues. It can also hydrate cyanamide to urea. CA2 is essential for bone resorption and osteoclast differentiation. CA2 plays vital role in the regulation of ion transport and pH balance and is involved in many biological processes. Moreover, CA2 downregulation promoted HCC metastasis and invasion. It serves as a suppressor of HCC metastasis and EMT and is correlated with favorable overall survival (OS) in HCC patients [1] [2] [3] [4] .

Carbonic anhydrase 2; Carbonic anhydrase C; CAC; CA-II; CA2

Greater than 95% as determined by reducing SDS-PAGE

Supplied as 0.22 μm filtered solution in PBS, pH 7.4.

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