protein

Biotinidase/BTD Protein, Human (HEK293, His)

HY-P72857

5 μg;10 μg;50 μg;100 μg

75;125;350;595 USD

Biotinidase/BTD Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

75;125;350;595 USD

Biotinidase is our subject of interest, playing a key role in the catalytic release of biotin from biocytin, a by-product formed during biotin-dependent carboxylase degradation. This enzymatic process is essential to recycle biotin, an important cofactor, and ensure its participation in various carboxylation reactions. Biotinidase/BTD Protein, Human (HEK293, His) is the recombinant human-derived Biotinidase/BTD protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Biotinidase/BTD Protein, Human (HEK293, His) is 502 a.a., with molecular weight of 75-90 kDa.

Human

Biotinidase, encoded by the BTD gene, is an enzyme that plays a crucial role in catalyzing the release of biotin from biocytin, which is the product of the degradation of biotin-dependent carboxylases. This enzymatic activity is essential for recycling biotin, a water-soluble B-vitamin, from biocytin, allowing it to be utilized again by biotin-dependent carboxylases in various metabolic pathways. Biotinidase deficiency, a rare genetic disorder, can lead to the impaired recycling of biotin, resulting in a range of neurological and cutaneous symptoms. The catalytic function of biotinidase underscores its significance in maintaining biotin homeostasis and ensuring the continuous availability of biotin for various biochemical processes in the cell.

Biotinidase; Biotinase; BTD

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.