protein

Bcl-XL Protein, Mouse (C-His)

HY-P72846A

5 μg;10 μg;50 μg;100 μg;500 μg

45;78;220;350;980 USD

Bcl-XL Protein, Mouse (C-His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg

45;78;220;350;980 USD

Bcl-XL protein forms heterodimers with BAX, BAK, or BCL2, but its antiapoptotic activity does not require heterodimerization with BAX. Bcl-XL Protein, Mouse (C-His) is the recombinant mouse-derived Bcl-XL, expressed by E. coli , with C-6*His labeled tag. The total length of Bcl-XL Protein, Mouse (C-His) is 212 a.a.,

Mouse

Bcl-XL protein forms heterodimers with BAX, BAK, or BCL2, with heterodimerization with BAX not being essential for its anti-apoptotic activity. Additionally, it interacts with isoform 1 of SIVA1, inhibiting its anti-apoptotic function. The protein also engages with IKZF3 and RTL10/BOP. Furthermore, interactions with DNM1L and CLTA suggest the potential formation of a complex in synaptic vesicles that includes clathrin and MFF. Notably, Bcl-XL interacts with NLRP1, specifically via the loop between motifs BH4 and BH3, but does not engage with NLRP2, NLRP3, NLRP4, PYCARD, or MEFV. It also interacts with BECN1, indicating its involvement in autophagy regulation.

Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; Bclx

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 10% trehalose, 0.02% Tween80.

Room temperature in continental US; may vary elsewhere.