protein

Hirudin Protein, Poecilobdella viridis (P. pastoris)

HY-P72799

10 μg;50 μg

128;360 USD

Hirudin Protein, Poecilobdella viridis (P. pastoris)

proteins

P. pastoris

10 μg;50 μg

128;360 USD

Hirudin Protein, a powerful thrombin-specific protease inhibitor, forms a stable non-covalent complex with alpha-thrombin, effectively preventing fibrinogen cleavage. This interaction underscores hirudin's critical role in regulating key coagulation cascade steps. Its specific thrombin inhibition emphasizes hirudin's significance as a therapeutic agent, particularly for precise blood clotting regulation. Hirudin Protein, Poecilobdella viridis (P. pastoris) is the recombinant Hirudin protein, expressed by P. pastoris , with tag free. The total length of Hirudin Protein, Poecilobdella viridis (P. pastoris) is 63 a.a., with molecular weight of ~6.7 kDa.

Others

Hirudin Protein emerges as a potent thrombin-specific protease inhibitor, showcasing its ability to form a stable non-covalent complex with alpha-thrombin. This interaction results in the effective abolition of alpha-thrombin's capacity to cleave fibrinogen, underscoring the critical role of hirudin in modulating key steps in the coagulation cascade. The specific and targeted inhibition of thrombin by hirudin highlights its significance as a therapeutic agent, particularly in contexts where precise regulation of blood clotting is essential.

Hirudin

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, pH 7.0, containing 2 % mannitol.

Room temperature in continental US; may vary elsewhere.