product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
AITRL/TNFSF18 Protein, Cynomolgus (HEK293, His)
catalog :
HY-P72773
quantity :
10 μg;50 μg
price :
80;210 USD
product information
Catalog Number :
HY-P72773
Product Name :
AITRL/TNFSF18 Protein, Cynomolgus (HEK293, His)
Product Type :
Protein
Host Species :
HEK293
Size :
10 μg;50 μg
List Price :
80;210 USD
Product Description :
AITRL, a type II transmembrane protein, is a ligand for glucocorticoid-induced TNFR-related protein (GITR). When AITRL binds to GITR, GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions. GITR/AITRL interaction plays a role in the pathogenesis of tumor, inflammation, as well as autoimmune diseases. Besides, AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1). AITRL/TNFSF18 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus AITRL (E74-S199) with C-terminal 6*His tag, which is expressed in HEK293.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA