protein

NGFR Protein, Human (HEK293)

HY-P7271

2 μg;10 μg;50 μg;100 μg

35;62;175;300 USD

NGFR Protein, Human (HEK293)

Protein

HEK293

2 μg;10 μg;50 μg;100 μg

35;62;175;300 USD

Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells.  NGFR Protein, Human (HEK293) is a recombinant protein consisting of 222 amino acids (K29-N250) and is produced in HEK293 cells.