protein

Dermatopontin/DPT Protein, Human (HEK293, Fc, His)

HY-P72667

10 μg;50 μg

125;320 USD

Dermatopontin/DPT Protein, Human (HEK293, Fc, His)

proteins

HEK293

10 μg;50 μg

125;320 USD

Dermatopontin/DPT Protein facilitates adhesion by binding to integrins on the cell surface. It acts as a conduit for communication between dermal fibroblast cells and the extracellular matrix. Furthermore, it enhances TGFB1 activity, inhibits cell proliferation, promotes collagen fibril formation, and stabilizes them at low temperatures. DPT Protein interacts with TGFB1, DCN, and collagen. Dermatopontin/DPT Protein, Human (HEK293, Fc, His) is the recombinant human-derived Dermatopontin/DPT protein, expressed by HEK293 , with C-hFc, C-6*His labeled tag. The total length of Dermatopontin/DPT Protein, Human (HEK293, Fc, His) is 183 a.a., with molecular weight of 50-60 kDa.

Human

The Dermatopontin/DPT protein is believed to facilitate adhesion through its binding to integrins on the cell surface. It may act as a conduit for communication between dermal fibroblast cells and their surrounding extracellular matrix. Additionally, it enhances the activity of TGFB1, inhibits cell proliferation, promotes the formation of collagen fibrils, and helps stabilize them against dissociation at low temperatures. The protein interacts with TGFB1, DCN, and collagen.

Dermatopontin; TRAMP; DPT

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 4% Sucrose, 4% mannitol, 0.02% Tween80, pH 7.5.

Room temperature in continental US; may vary elsewhere.