protein

FGF-4 Protein, Mouse

HY-P72649

2 μg;10 μg;50 μg;100 μg;500 μg

30;80;220;360;1180 USD

FGF-4 Protein, Mouse

proteins

E. coli

2 μg;10 μg;50 μg;100 μg;500 μg

30;80;220;360;1180 USD

The FGF-4 protein plays a key role in embryonic development and is central to cell proliferation and differentiation. It is essential for the survival of mouse embryos after implantation and is key to normal limb and heart valve development. FGF-4 Protein, Mouse is the recombinant mouse-derived FGF-4 protein, expressed by E. coli , with tag free.

Mouse

FGF-4 Protein assumes a pivotal role in shaping embryonic development, acting as a central regulator of cell proliferation and differentiation. Its indispensability is underscored by its essential role in ensuring the survival of postimplantation mouse embryos. During embryogenesis, FGF-4 is a key player in orchestrating normal limb and cardiac valve development, reflecting its diverse impact on tissue morphogenesis. Additionally, FGF-4 may contribute to the intricate process of embryonic molar tooth bud development by inducing the expression of MSX1, MSX2, and SDC1 in dental mesenchyme cells. This versatile protein engages in interactions with FGFR1, FGFR2, FGFR3, and FGFR4, forming molecular partnerships that underpin its multifaceted functions. The cooperative binding with heparan sulfate glycosaminoglycans enhances the affinity between FGF-4 and its receptors, adding a layer of complexity to its regulatory mechanisms.

Fibroblast growth factor 4; FGF-4; HBGF-4; HST

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.