protein

Follistatin-like 1/FSTL1 Protein, Human (His)

HY-P72640

10 μg;50 μg

107;300 USD

Follistatin-like 1/FSTL1 Protein, Human (His)

proteins

E. coli

10 μg;50 μg

107;300 USD

Follistatin-like 1 (FSTL1) protein is a secreted glycoprotein that contributes to angiogenesis, immune response regulation, and cell proliferation. It aids in the development of the central nervous system, skeletal system, lungs and ureters. Follistatin-like 1/FSTL1 Protein, Human (His) is the recombinant human-derived Follistatin-like 1/FSTL1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of Follistatin-like 1/FSTL1 Protein, Human (His) is 288 a.a., with molecular weight of 30-38 kDa.

Human

Follistatin-like 1 (FSTL1) protein is a secreted glycoprotein that plays a role in various physiological processes, including angiogenesis, immune response regulation, cell proliferation, and differentiation. It is involved in the development of the central nervous system, skeletal system, lungs, and ureter. FSTL1 promotes endothelial cell survival, migration, and differentiation into network structures through an AKT-dependent mechanism. It also supports the survival of cardiac myocytes. FSTL1 initiates different signaling cascades by activating various receptors on the cell surface, such as DIP2A, TLR4, or BMP receptors. It forms homodimers and interacts with SCN10A. FSTL1 also interacts with DIP2A, which may act as a cell surface receptor for FSTL1. Additionally, FSTL1 interacts with BMP4 and CD14, with the latter interaction promoting TLR4-mediated signaling cascade.

Follistatin-related protein 1; Follistatin-like protein 1; FSTL1; FRP

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.