product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
IgG2B Fc Protein, Mouse (HEK293)
catalog :
HY-P72602
quantity :
10 μg;50 μg
price :
30;85 USD
product information
Catalog Number :
HY-P72602
Product Name :
IgG2B Fc Protein, Mouse (HEK293)
Product Type :
proteins
Host Species :
HEK293
Size :
10 μg;50 μg
List Price :
30;85 USD
Product Description :
IgG2B Fc Protein is a member of many immunoglobulin G developed and secreted by effective B cells [1] . IgG2B Fc Protein, Mouse (HEK293) is the recombinant mouse-derived IgG2B Fc protein, expressed by HEK293 , with tag free. The total length of IgG2B Fc Protein, Mouse (HEK293) is 239 a.a., with molecular weight of 30-32 kDa.
SpeciesSummary :
Mouse
Background :
IgG2B Fc Protein is a member of many immunoglobulin G developed and secreted by effective B cells [1] . In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment [2] [3] . The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement [4] . The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3) [5] .
ALTnames :
Ig gamma-2B chain C region; IgG2B Fc; Igh-3
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Buffer :
Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
Storage :
Room temperature in continental US; may vary elsewhere.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA