protein

IL-16 Protein, Mouse (His)

HY-P72590

10 μg;50 μg

168;504 USD

IL-16 Protein, Mouse (His)

proteins

E. coli

10 μg;50 μg

168;504 USD

IL-16 Protein, a cytokine, plays a significant role in immune regulation and inflammation. It modulates the activation and migration of various immune cells, such as T cells and monocytes. Understanding the functions of IL-16 Protein can aid in studying immune responses and developing targeted therapies for inflammatory and autoimmune diseases. IL-16 Protein, Mouse (His) is the recombinant mouse-derived IL-16 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-16 Protein, Mouse (His) is 118 a.a., with molecular weight of 14-16 kDa.

Mouse

IL-16, a multifaceted protein, instigates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. It plays a pivotal role in priming CD4+ T-cells for responsiveness to interleukin-2 (IL-2) and interleukin-15 (IL-15), concurrently inducing the expression of the interleukin 2 receptor. Additionally, IL-16 serves as a ligand for CD4, fostering intricate interactions. Notably, isoform 1 of IL-16 is proposed to function as a scaffolding protein, providing a structural anchor for ion channels within the cellular membrane.

Pro-interleukin-16; Interleukin-16; IL-16; Lymphocyte chemoattractant factor; LCF

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

Room temperature in continental US; may vary elsewhere.