protein

IL-21R Protein, Mouse (HEK293, His)

HY-P72560

10 μg;50 μg

105;295 USD

IL-21R Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg;50 μg

105;295 USD

The IL-21R protein is specifically designed for IL-21 and forms a heterodimeric complex with the common γ subunit, which is critical for signal transduction. This receptor complex promotes interaction with Janus kinase 1 (JAK1), initiating downstream signaling events in response to interleukin-21. IL-21R Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-21R protein, expressed by HEK293 , with C-6*His labeled tag.

Mouse

IL-21R Protein functions as a receptor specifically designed for interleukin-21, forming a heterodimeric complex with the common gamma subunit. This receptor complex, crucial for transducing signals initiated by interleukin-21, enables cellular responses to this cytokine. The IL-21R heterodimeric structure facilitates its interaction with Janus kinase 1 (JAK1), playing a pivotal role in initiating downstream signaling events in response to interleukin-21 binding. The association of IL-21R with the common gamma subunit and its interaction with JAK1 collectively contribute to the transduction of interleukin-21-mediated signals, thus influencing various cellular processes and immune responses.

Interleukin-21 receptor; IL-21 receptor; IL-21R; CD360; Nilr

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.