protein

IL-36 alpha/IL-1F6 Protein, Mouse

HY-P72547

2 μg;10 μg;20 μg;50 μg;100 μg;500 μg;1 mg

32;82;130;250;425;1200;1750 USD

IL-36 alpha/IL-1F6 Protein, Mouse

Protein

E. coli

2 μg;10 μg;20 μg;50 μg;100 μg;500 μg;1 mg

32;82;130;250;425;1200;1750 USD

IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-κB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases. IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP. IL-36 alpha/IL-1F6 Protein, Mouse is a recombinant mouse IL-36 alpha without any tag, which is produced in E. coli.