protein

LILRB1/CD85j/ILT2 Protein, Rhesus Macaque (HEK293, His)

HY-P72520

5 μg;10 μg;50 μg

35;50;110 USD

LILRB1/CD85j/ILT2 Protein, Rhesus Macaque (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

35;50;110 USD

LILRB1/CD85j/ILT2 Protein is an inhibitory receptor broadly expressed on leukocytes and recognizes HLA-class I and human cytomegalovirus UL18 [1] . LILRB1/CD85j/ILT2 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived LILRB1/CD85j/ILT2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LILRB1/CD85j/ILT2 Protein, Rhesus Macaque (HEK293, His) is 440 a.a., with molecular weight of 60-85 kDa.

Rhesus Macaque

LILRB1/CD85j/ILT2 Protein a member of the leukocyte immunoglobulin-like receptor (LIR) family which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) [2] . LILRB1/CD85j/ILT2 Protein is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity [3] .

Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; LILRB1; CD85j; ILT2; LIR-1; MIR7

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.