protein

CD31/PECAM-1 Protein, Human (HEK293, His)

HY-P72490

10 μg;50 μg

72;180 USD

CD31/PECAM-1 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

72;180 USD

CD31/PECAM-1 Protein is a cell-cell adhesion protein that is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions [1] [2] . CD31/PECAM-1 Protein, Human (HEK293, His) is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with C-6*His labeled tag.

Human

CD31/PECAM-1 Protein is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils [1] [2] . CD31/PECAM-1 Protein binds to itself homotypically, and also to the leukocyte integrin alpha v beta 3 heterotypically [3] . CD31/PECAM-1 Protein is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells [4] .

Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, 1 mM EDTA, pH 7.4 .

Room temperature in continental US; may vary elsewhere.