protein

IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi)

HY-P72378

20 μg;100 μg

285;800 USD

IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi)

proteins

HEK293

20 μg;100 μg

285;800 USD

The IGFBP-5 protein regulates insulin-like growth factor (IGF) and extends its lifespan. It can inhibit or stimulate the growth-promoting effect of IGF, showing its dual regulatory function. IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IGFBP-5 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of IGFBP-5 Protein, Human (Biotinylated, HEK293, His-Avi) is 252 a.a., with molecular weight of 32-45 kDa.

Human

IGFBP-5 protein assumes a crucial role in regulating the activity of insulin-like growth factors (IGFs) by extending their half-life. Within cell culture, IGFBP-5 has demonstrated the ability to either inhibit or stimulate the growth-promoting effects of IGFs. This dual regulatory function underscores the complexity of IGFBP-5's influence on cellular processes. Importantly, IGFBP-5 achieves these effects by modulating the interaction between IGFs and their cell surface receptors, thereby fine-tuning the signaling pathways associated with growth and development. The intricate interplay between IGFBP-5 and IGFs highlights the nuanced control mechanisms that govern cellular responses to growth factors, offering insights into the multifaceted role of IGFBP-5 in the regulation of cellular growth and proliferation.

Insulin-Like Growth Factor-Binding Protein 5; IBP-5; IGF-Binding Protein 5; IGFBP-5; IGFBP5; IBP5

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.