protein

Protein L1/L1R, Vaccinia virus (Sf9, His, myc)

HY-P72301

2 μg;10 μg;50 μg

69;175;365 USD

Protein L1/L1R, Vaccinia virus (Sf9, His, myc)

proteins

Sf9 insect cells

2 μg;10 μg;50 μg

69;175;365 USD

Protein L1/L1R is part of the entry fusion complex (EFC) composed of 11 proteins. This complex facilitates the entry of the virion core into the host cytoplasm through a two-step process: lipid mixing of viral and cellular membranes, followed by pore formation. The assembly or stability of the EFC relies on all proteins except OPG095 and OPG053. Protein L1/L1R, Vaccinia virus (Sf9, His, myc) is the recombinant Virus-derived protein L1/L1R, expressed by Sf9 insect cells , with N-His, C-Myc labeled tag. The total length of Protein L1/L1R, Vaccinia virus (Sf9, His, myc) is 182 a.a., with molecular weight of ~27 kDa.

Virus

Protein L1/L1R plays a vital role as a component of the entry fusion complex (EFC), a critical assembly of 11 proteins that facilitates the entry of the virion core into the host cytoplasm during cell infection. The EFC orchestrates this process through a two-step mechanism involving lipid mixing of the viral and cellular membranes, followed by the formation of a pore. Within the EFC, Protein L1/L1R collaborates with other proteins, namely OPG053, OPG076, OPG086, OPG094, OPG099, OPG107, OPG143, OPG104, OPG147, and OPG155. Notably, with the exception of OPG095 and OPG053, each protein within the EFC is indispensable for the assembly or stability of the complex.

Virion membrane protein M25

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.