protein

Clumping factor B Protein, S. aureus (His)

HY-P72291

2 μg;10 μg;50 μg

58;145;305 USD

Clumping factor B Protein, S. aureus (His)

proteins

E. coli

2 μg;10 μg;50 μg

58;145;305 USD

Clumping factor B (ClfB) is a cell surface-associated protein implicated in virulence, playing a crucial role in bacterial pathogenicity by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen. Its significance lies in inducing the formation of bacterial clumps, a mechanism that contributes to the pathogenicity and virulence of the bacteria. Clumping factor B Protein, S. aureus (His) is the recombinant Staphylococcus aureus-derived Clumping factor B protein, expressed by E. coli , with N-His labeled tag. The total length of Clumping factor B Protein, S. aureus (His) is 498 a.a., with molecular weight of ~80 kDa.

Staphylococcus aureus

Clumping factor B (ClfB) is a cell surface-associated protein crucial for bacterial virulence, as it plays a pivotal role in promoting bacterial attachment. It specifically binds to both alpha- and beta-chains of human fibrinogen, facilitating the formation of bacterial clumps. This interaction is significant in the context of host-pathogen interactions, as it enhances the adherence of bacteria to fibrinogen, contributing to the pathogenicity of the organism. The ability of ClfB to induce bacterial clumps suggests its involvement in the early stages of infection and highlights its potential as a target for therapeutic interventions aimed at disrupting bacterial adherence and virulence (

Fibrinogen receptor B; Fibrinogen-binding protein B

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.