protein

Nucleoprotein/NP Protein, Influenza A virus H3N2 (His-SUMO)

HY-P72285

2 μg;10 μg;50 μg

58;145;305 USD

Nucleoprotein/NP Protein, Influenza A virus H3N2 (His-SUMO)

proteins

E. coli

2 μg;10 μg;50 μg

58;145;305 USD

The Nucleoprotein/NP Protein in the influenza virus is crucial for viral replication and transcription. It binds to viral RNA, forming a ribonucleoprotein complex necessary for genome replication. NP Protein also interacts with host proteins, facilitating viral pathogenesis and immune evasion. Understanding NP Protein's functions can aid in developing antiviral strategies against influenza infections. Nucleoprotein/NP Protein, Influenza A virus H3N2 (His-SUMO) is the recombinant Virus-derived Nucleoprotein/NP protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of Nucleoprotein/NP Protein, Influenza A virus H3N2 (His-SUMO) is 498 a.a., with molecular weight of ~72.0 kDa.

Virus

Furthermore, the protein plays a role in repressing the innate antiviral response by facilitating the formation of the NMI-IFI35 complex through ubiquitination of NMI. During viral infection, it promotes cell pyroptosis by mediating ubiquitination of ISG12a/IFI27 and facilitating its translocation into the mitochondria, leading to CASP3 activation. It also mediates polyubiquitination of G3BP1 in response to heat shock, resulting in stress granule disassembly.

NP; Nucleoprotein; Nucleocapsid protein; Protein N

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.