protein

Protein E7, HPV16 (His)

HY-P72259

2 μg;5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;65;100;282;480;1350;2150 USD

Protein E7, HPV16 (His)

Protein

E. coli

2 μg;5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;65;100;282;480;1350;2150 USD

HPV16 E7 is a viral phosphoprotein with oncogenic activity, belonging to the human papillomavirus early protein family. HPV16 E7 activates the cell cycle by releasing E2F through proteasome degradation of pRB. HPV16 E7 can cooperate with E6 to immortalize cells and neutralize the toxicity of E5, while activating the AP-1/NF-κB pathway and downregulating E-cadherin to enhance migration and invasion, making it a core target for cervical cancer. Protein E7, HPV (His) is a recombinant HPV E7 protein expressed from E. coli with an N-6*His tag.