protein

HAMP protein, Larimichthys crocea

HY-P72221

5 μg;10 μg;50 μg

200;350;600 USD

HAMP protein, Larimichthys crocea

proteins

E. coli

5 μg;10 μg;50 μg

200;350;600 USD

HAMP protein is a key signaling molecule for iron homeostasis and cooperates with HFE to regulate intestinal iron absorption and macrophage iron storage. HAMP has significant antibacterial effects and shows strong antibacterial activity against Gram-negative bacteria such as Vibrio alginolyticus and Gram-positive bacteria such as Staphylococcus aureus. HAMP protein, Larimichthys crocea is the recombinant HAMP protein, expressed by E. coli , with tag free. The total length of HAMP protein, Larimichthys crocea is 21 a.a., with molecular weight of ~2.5 kDa.

Others

HAMP protein appears to function as a signaling molecule crucial for maintaining iron homeostasis, working in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. Its antimicrobial properties are notable, demonstrating robust antibacterial activity against various Gram-negative bacteria, including V.alginolyticus, V.fluvialis, V.harveyis, and V.parahaemolyticus, with varying minimum inhibitory concentrations (MICs). Additionally, HAMP displays antibacterial activity against Gram-positive bacteria such as B.cereus, B.subtilis, C.glutamicum, M.luteus, M.lysodeikticus, S.aureus, and S.epidermis. Furthermore, it exhibits antifungal activity against A.niger, F.graminearum, and F.solani, while lacking antifungal effects against the yeasts P.pastoris GS115 and C.albicans. These diverse activities underscore the multifaceted role of HAMP in host defense mechanisms against microbial challenges.

hamp; Hepcidin

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm solution of PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US;may vary elsewhere.