protein

FOXM1 Protein, Human (His, SUMO-Myc)

HY-P72197

5 μg;10 μg;50 μg

88;150;420 USD

FOXM1 Protein, Human (His, SUMO-Myc)

proteins

E. coli

5 μg;10 μg;50 μg

88;150;420 USD

FOXM1 is an important transcription factor that controls cell cycle gene expression critical for DNA replication and mitosis, underscoring its critical role in cellular processes. In addition to cell proliferation, FOXM1 contributes to DNA break repair and DNA damage checkpoint responses. FOXM1 Protein, Human (His, SUMO-Myc) is the recombinant human-derived FOXM1 protein, expressed by E. coli , with N-10*His, C-Myc, N-SUMO labeled tag.

Human

FOXM1, a crucial transcription factor, governs the expression of cell cycle genes vital for DNA replication and mitosis, underscoring its pivotal role in orchestrating cellular processes. Beyond its involvement in cell proliferation control, FOXM1 also contributes to DNA break repair, actively participating in the DNA damage checkpoint response. Notably, FOXM1 promotes the transcription of PHB2, emphasizing its diverse regulatory functions. Furthermore, FOXM1 interacts with PINT87aa, a product encoded by the circular form of the long non-coding RNA LINC-PINT, and this interaction serves to inhibit FOXM1-mediated transcription of PHB2, revealing an intricate layer of regulatory control in cellular transcriptional processes.

FKHL16; Forkhead box M1; Forkhead box protein M1; forkhead like 16; Forkhead-related protein FKHL16; FOX M1; Foxm1; FOXM1_HUMAN; FOXM1B; HFH-11; HFH11; HNF-3/fork-head homolog 11; HNF3; INS1; M phase phosphoprotein 2; M-phase phosphoprotein 2; MPHOSPH2; MPP2; PIG29; TGT3; Transcription factor Trident; Trident; WIN; Winged-helix factor from INS1 cells

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl,0.5 M NaCl, 6% Trehalose, pH 8.0

Room temperature in continental US;may vary elsewhere.