protein

IL-33 Protein, Mouse

HY-P7218

2 μg;10 μg;50 μg;100 μg

35;80;240;408 USD

IL-33 Protein, Mouse

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

35;80;240;408 USD

377622352

IL-33 Protein, Mouse is a tissue-derived nuclear cytokine from the IL-1 family abundantly expressed in endothelial cells, epithelial cells and fibroblast-like cells, both during homeostasis and inflammation.

Mouse

Interleukin-33 (IL-33) was originally described as an inducer of type 2 immune responses, activating T helper 2 cells and mast cells. Evidence shows that IL-33 also potently stimulates group 2 innate lymphoid cells, regulatory T cells, TH1 cells, CD8+ T cells and natural killer cells [1] . IL-33 is a crucial immune modulator with pleiotropic activities in type-2, type-1 and regulatory immune responses, and important roles in allergic, fibrotic, infectious, and chronic inflammatory diseases [2] .

rMuIL-33; Il33

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS, 1 mM DDT, pH 7.4 or PBS, 1 mM EDTA or PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.