protein

DBI Protein, Human (103a.a, His)

HY-P72166

5 μg;10 μg;50 μg;100 μg

68;116;325;550 USD

DBI Protein, Human (103a.a, His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

68;116;325;550 USD

DBI, a versatile protein, binds medium- and long-chain acyl-CoA esters, indicating a potential intracellular carrier role. It also displaces diazepam from the benzodiazepine recognition site on the GABA type A receptor. This dual functionality suggests DBI may act as a neuropeptide, modulating GABA receptor activity. Remarkably, DBI functions as a monomer in these interactions. DBI Protein, Human (103a.a, His) is the recombinant human-derived DBI protein, expressed by E. coli , with N-6*His labeled tag. The total length of DBI Protein, Human (103a.a, His) is 103 a.a., with molecular weight of ~14 kDa.

Human

DBI, a versatile protein, exhibits a remarkable affinity for binding medium- and long-chain acyl-CoA esters, suggesting its potential role as an intracellular carrier for these molecules. Additionally, DBI demonstrates the ability to displace diazepam from the benzodiazepine (BZD) recognition site situated on the GABA type A receptor. This intriguing dual functionality raises the possibility that DBI serves as a neuropeptide, exerting modulation on the activity of the GABA receptor. Notably, DBI functions as a monomer in carrying out these interactions.

ACBD1; ACBP; ACBP_HUMAN; Acyl CoA binding domain containing 1; Acyl CoA binding protein; Acyl Coenzyme A binding domain containing 1; Acyl coenzyme A binding protein; Acyl-CoA-binding protein; CCK RP; CCKRP; Cholecystokinin releasing peptide trypsin sensitive; DBI; Diazepam-binding inhibitor; Endozepine; EP; GABA receptor modulator; MGC70414

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.